After Hetty's guardian was killed in a fire and she was left penniless, William Herrick attempted to sell Hetty to a brothel, but was recruited by her.
In 2008, following Herrick's death and the subsequent failure of Herrick's global Vampire revolution, Hetty met with Ivan and Daisy Hannigan-Spiteri at a pub in Singapore and discussed the situation there with them, before leaving to ship out to Bolivia to join the other Old Ones. (Ivan and Daisy)
At the time when the Old Ones chose to initiate a global Vampire takeover as a result of the repercussions of the Box Tunnel 20 Massacre, Hetty and the other Old Ones travelled by freighter from Bolivia across the Atlantic Ocean to Barry Island, to discuss their plans there, and set up base at Barry in Stoker Import and Exports. When Hal and Tom McNair arrived and threatened to blow up Stoker's and kill the Old Ones there, Hetty and another Old One slipped out and left. ("The War Child")
Within the next two months, Hetty was captured and detained by the Department of Domestic Defence. Two months after the deaths of the other Old Ones when Stoker's was blown up shortly after Hetty left, Hetty revealed Hal's existence to Dominic Rook, and agreed to tell Rook everything she knew about Hal in exchange for a flight back to Bolivia the next day. ("The Trinity")
- Hetty has been portrayed by three different actors, one in each series, most likely due to the actors' young ages resulting in them aging between series and looking too different to reprise their roles as Hetty.
- Hetty was the vampire that recruited Herrick (who attempted a Vampire takeover in Series 1 and 3), who in turn was the vampire that recruited John Mitchell (who in turn committed the Box Tunnel 20 Massacre; which had many repercussions throughout Series 3 and 4, including the Old Ones' decision to attempt a global vampire takeover). Due to this, it can be argued that Hetty is indirectly responsible for the majority of the events of the first four series of Being Human. Also, because she alerted Rook to the fact that Hal was alive, it could be said that every event in the show was indirectly Hetty's fault.